⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098714 | 0.72 | NPC1 (0.35) | — | |
| SCHEMBL1080070 | 0.72 | — | — | |
| SCHEMBL149636 | 0.72 | — | — | |
| SCHEMBL31134168 | 0.69 | — | — | |
| SCHEMBL457503 | 0.67 | — | — | |
| SCHEMBL1427905 | 0.67 | ENPP2 (0.42) | — | |
| SCHEMBL29776734 | 0.67 | — | — | |
| SCHEMBL14204907 | 0.67 | — | — | |
| SCHEMBL199726 | 0.67 | — | — | |
| SCHEMBL4810613 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 880 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3984996-B1 | AMINO PYRIMIDINE SSAO INHIBITORS | LILLY CO ELI (US) | 2024-10-09 | — | — | EP | claimed |
| CN-117658885-A | Benzyloxy aryl compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-03-08 | — | — | CN | claimed |
| CN-116903544-A | Preparation method of olanzapine and intermediate thereof | 江苏丽源医药有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-114380801-A | Aminopyrimidine SSAO inhibitors and methods of making the same | 伊莱利利公司 | 2022-04-22 | — | — | CN | claimed |
| EP-3984996-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | Eli Lilly and Company (US) | 2022-04-20 | — | — | EP | claimed |
| US-10793552-B2 | Amino pyrimidine ssao inhibitors | ELI LILLY AND COMPANY (US) | 2020-10-06 | — | — | US | claimed |
| US-20200262817-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2020-08-20 | — | — | US | claimed |
| US-10464928-B2 | Amino pyrimidine SSAO inhibitors | ELI LILLY AND COMPANY (US) | 2019-11-05 | — | — | US | claimed |
| US-20190276436-A1 | AMINO PYRIMIDINE SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2019-09-12 | — | — | US | claimed |
| CN-110041269-A | A kind of preparation method of the chloro- 5- hydroxy pyrimidine of 2- | 海门瑞一医药科技有限公司 | 2019-07-23 | — | — | CN | claimed |
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | claimed |
| EP-4225762-B1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| CN-122079879-A | Nitrogen-containing heterocyclic derivative inhibitor, preparation method and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122079878-A | Nitrogen-containing heterocyclic derivative inhibitor, preparation method and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| EP-0658548-B1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5589478-A | ENDOTHELIN ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| CN-1111242-A | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO (JP) | 1995-11-08 | — | — | CN | disclosed |
| EP-0658548-A1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-3988457-A | B-NAPHTHYLMETHYL PIPERAZINYL DERIVATIVES | SMITHKLINE CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |