Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 9/20 | 0.49 |
| ▸ | CSF1R | P07333 | 4/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | FLT1 | P17948 | 3/20 | 0.42 |
| ▸ | FLT4 | P35916 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | LYN | P07948 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13096862 | 0.86 | MAOB (0.43) | LCLAT1KDRCSF1RPDGFRBROCK2 | |
| SCHEMBL13097082 | 0.86 | KDR (0.57) | KDRCSF1RPDGFRBROCK2KIT | |
| SCHEMBL1499248 | 0.83 | KDR (0.53) | LCLAT1KDRCSF1RPDGFRBLCK | |
| SCHEMBL13097007 | 0.82 | MEN1 (0.51) | KDRCSF1RKITFLT1FLT4 | |
| SCHEMBL12322152 | 0.81 | MMP9 (0.50) | KDRLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL1499270 | 0.79 | KDR (0.41) | KDRCSF1RPDGFRBKITFGFR1 | |
| SCHEMBL12322989 | 0.78 | KDR (0.60) | KDRCSF1RROCK2KITFGFR1 | |
| SCHEMBL13097211 | 0.77 | BRAF (0.54) | KDRCSF1RPDGFRBROCK2KIT | |
| SCHEMBL4232674 | 0.76 | KDR (0.82) | KDRCSF1RROCK2KITFGFR1 | |
| SCHEMBL13799953 | 0.76 | LCLAT1 (0.52) | LCLAT1KDRCSF1RPDGFRBROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261730-A1 | ALKYNYLARYL COMPOUNDS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-10-14 | — | — | US | disclosed |
| EP-2070929-A1 | Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261730-A1 | ALKYNYLARYL COMPOUNDS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME | ALK, ALKBH3, EDNRB | LCLAT1 2119/4885KDR 6/4885CSF1R 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.