Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097024 | 0.85 | MAPK1 (0.64) | MAOBFFAR1SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL17912866 | 0.83 | NPC1 (0.60) | LTA4HMAOBFFAR1NPC1 | |
| SCHEMBL6910779 | 0.81 | FFAR1 (0.60) | MAOBFFAR1CYP4F2CYP4A11BCHE | |
| SCHEMBL13097043 | 0.81 | LTA4H (0.53) | LTA4HFFAR1SMN1; SMN2SLC2A1TLR4 | |
| SCHEMBL13097044 | 0.81 | MAPT (0.43) | LTA4HMAOBFFAR1SMN1; SMN2ABCB1 | |
| SCHEMBL13097032 | 0.81 | ALDH1A1 (0.61) | MAOBFFAR1SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL8783402 | 0.80 | F2 (0.63) | LTA4HFFAR1SMN1; SMN2ABCB1BCHE | |
| SCHEMBL13462936 | 0.80 | LTA4H (0.55) | LTA4HSMN1; SMN2SLC2A1MAPK1 | |
| SCHEMBL13107288 | 0.80 | LTA4H (0.55) | LTA4HSMN1; SMN2SLC2A1NPC1 | |
| SCHEMBL4569962 | 0.80 | F2 (0.60) | LTA4HMAOBFFAR1SMN1; SMN2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | LTA4H 421/4885MAOB 200/4885FFAR1 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.