Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097058 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3ALOX5FFAR4 | |
| SCHEMBL13106640 | 0.81 | GRIN1 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1FFAR4 | |
| SCHEMBL8322225 | 0.80 | MAOB (0.58) | MAOBGRM5ALDH1A1ALOX5MAOA | |
| SCHEMBL1263059 | 0.79 | AGXT (0.61) | MAOBGRM5ALDH1A1ALOX5PRKDC | |
| SCHEMBL3103344 | 0.79 | MAOB (0.57) | MAOBGRM5ALDH1A1ALOX5MAOA | |
| SCHEMBL13097316 | 0.78 | PRMT5 (0.52) | MAOBGRM5ALDH1A1ALOX5KDM4E | |
| SCHEMBL13097056 | 0.77 | DRD2 (0.44) | SLC6A2SLC6A4SLC6A3FFAR4SMN1; SMN2 | |
| SCHEMBL32665315 | 0.75 | MAOB (0.49) | MAOBGRM5ALDH1A1ALOX5FFAR4 | |
| SCHEMBL737235 | 0.75 | MAPT (0.49) | SLC6A2SLC6A3MAOBALDH1A1MAOA | |
| SCHEMBL4671542 | 0.74 | ALOX5 (0.54) | MAOBGRM5ALDH1A1ALOX5MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | SLC6A2 1834/4885SLC6A4 2561/4885SLC6A3 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.