Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106539 | 0.91 | PIK3CG (0.37) | DHODHPIK3CAPIK3CGMAPTKCNH2 | |
| SCHEMBL13097186 | 0.90 | DHODH (0.39) | DHODHPIK3CAPIK3CGMRGPRX4RORC | |
| SCHEMBL13097189 | 0.88 | RORC (0.41) | DHODHRORCMAPTALDH1A1 | |
| SCHEMBL13097199 | 0.84 | CHRM4 (0.42) | DHODHRORCKCNH2 | |
| SCHEMBL13107310 | 0.81 | AKT1 (0.36) | DHODHPIK3CAPIK3CGMAPT | |
| SCHEMBL13097126 | 0.80 | RORC (0.42) | DHODHRORCPTGER1MAPTALDH1A1 | |
| SCHEMBL13097143 | 0.79 | HRH3 (0.44) | DHODHRORCMAPTALDH1A1 | |
| SCHEMBL13097203 | 0.78 | CHRM4 (0.46) | RORCMAPTKCNH2 | |
| SCHEMBL13107227 | 0.78 | OGG1 (0.39) | RORCKCNH2IDO1 | |
| SCHEMBL13097194 | 0.78 | RORC (0.45) | RORCMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | DHODH 294/4885PIK3CA 681/4885PIK3CG 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.