Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106293 | 0.90 | GRM4 (0.39) | GABRA5CYP2D6GRM4HTTSMN1; SMN2 | |
| SCHEMBL13097261 | 0.87 | CYP2D6 (0.43) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 | |
| SCHEMBL13097266 | 0.87 | CYP2D6 (0.49) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 | |
| SCHEMBL13097245 | 0.87 | GABRA5 (0.39) | GABRA5CYP2D6MAPTALDH1A1TDP1 | |
| SCHEMBL3109558 | 0.86 | CYP2D6 (0.54) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 | |
| SCHEMBL13097212 | 0.85 | GABRA5 (0.40) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 | |
| SCHEMBL13097246 | 0.84 | GABRA5 (0.39) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 | |
| SCHEMBL13097269 | 0.83 | GABRA5 (0.41) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 | |
| SCHEMBL13097270 | 0.83 | CYP2D6 (0.42) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 | |
| SCHEMBL13097301 | 0.83 | GABRA5 (0.40) | GABRA5CYP2D6STAT3HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | GABRA5 3532/4885CYP2D6 230/4885GRM4 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.