Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106592 | 0.90 | CYP2D6 (0.42) | CYP2D6GABRA5HTTSMN1; SMN2MAPT | |
| SCHEMBL3109558 | 0.90 | CYP2D6 (0.54) | CYP2D6GABRA5HTTSMN1; SMN2STAT3 | |
| SCHEMBL13096832 | 0.89 | CYP2D6 (0.50) | CYP2D6HTTSMN1; SMN2STAT3MAPT | |
| SCHEMBL13097266 | 0.87 | CYP2D6 (0.49) | CYP2D6GABRA5HTTSMN1; SMN2STAT3 | |
| SCHEMBL13097229 | 0.87 | GABRA5 (0.42) | CYP2D6GABRA5HTTSMN1; SMN2STAT3 | |
| SCHEMBL13097270 | 0.84 | CYP2D6 (0.42) | CYP2D6GABRA5HTTSMN1; SMN2STAT3 | |
| SCHEMBL13097245 | 0.82 | GABRA5 (0.39) | CYP2D6GABRA5MAPTTDP1 | |
| SCHEMBL3098716 | 0.81 | PDE2A (0.39) | CYP2D6GABRA5MAOA | |
| SCHEMBL13097269 | 0.80 | GABRA5 (0.41) | CYP2D6GABRA5HTTSMN1; SMN2STAT3 | |
| SCHEMBL13097301 | 0.80 | GABRA5 (0.40) | CYP2D6GABRA5HTTSMN1; SMN2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | CYP2D6 230/4885GABRA5 3532/4885HTT 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.