SCHEMBL13097277

SCHEMBL13097277

Cc1ccc(-n2cc(Cl)cn2)cc1C1=C(O)C2(CCCCC2)CC1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RIPK2 O43353 17/20 0.33
P2RX7 Q99572 1/20 0.31
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13097065 0.81 ACACB (0.48) RIPK2P2RX7ACACBACACA
SCHEMBL13097293 0.81 MEN1 (0.38) RIPK2
SCHEMBL13097119 0.80 NPY5R (0.32) RIPK2ACACBACACA
SCHEMBL2355616 0.76 ACACB (0.50) ACACBACACA
SCHEMBL13097072 0.76 RIPK2 (0.33) RIPK2ACACBACACA
SCHEMBL2348232 0.75 ACACB (0.51) ACACBACACA
SCHEMBL12129152 0.74 ALDH1A1 (0.32) RIPK2ACACBACACA
SCHEMBL2354347 0.74 PGR (0.44) ACACBACACA
SCHEMBL14395135 0.73 BIRC5 (0.34) ACACBACACA
SCHEMBL2356712 0.73 ACACB (0.40) ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267964-A1 N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS FISCHER REINER 2010-10-21 US disclosed
US-20100267964-A1 N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS FISCHER REINER 2010-10-21 US disclosed
US-7776791-B2 N-heterocyclyl phenyl-substituted cyclic ketoenols BAYER CROPSCIENCE AG (DE) 2010-08-17 US disclosed
US-7776791-B2 N-heterocyclyl phenyl-substituted cyclic ketoenols BAYER CROPSCIENCE AG (DE) 2010-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267964-A1 N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS CYP17A1, CCNY, CCNE2 RIPK2 3998/4885P2RX7 2789/4885ACACB 474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.