Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GCG | P01275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097315 | 0.91 | DRD2 (0.34) | DRD2DRD4 | |
| SCHEMBL13097101 | 0.85 | DRD2 (0.36) | DRD2DRD4HPGDTP53 | |
| SCHEMBL13097303 | 0.83 | KDM4E (0.34) | DRD2DRD4KDM4EALDH1A1HPGD | |
| SCHEMBL13527336 | 0.80 | SMN1; SMN2 (0.32) | NPSR1TP53 | |
| SCHEMBL12658307 | 0.75 | FGFR1 (0.35) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL13097086 | 0.75 | ALDH1A1 (0.30) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL13176552 | 0.74 | CYP3A4 (0.31) | ALDH1A1 | |
| SCHEMBL10309321 | 0.70 | SSTR4 (0.31) | — | |
| SCHEMBL13527335 | 0.70 | KMT2A (0.34) | ALDH1A1NPSR1 | |
| SCHEMBL13527338 | 0.67 | CNR1 (0.34) | NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267964-A1 | N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS | FISCHER REINER | 2010-10-21 | — | — | US | disclosed |
| US-7776791-B2 | N-heterocyclyl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267964-A1 | N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS | CYP17A1, CCNY, CCNE2 | DRD2 4492/4885DRD4 3862/4885KDM4E 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.