Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106336 | 0.90 | ADAM17 (0.38) | MAPTPIK3CDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13097431 | 0.86 | NAAA (0.46) | MAPTRAB9ASMN1; SMN2NPC1MGLL | |
| SCHEMBL3091096 | 0.85 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2NPC1MGLL | |
| SCHEMBL13097461 | 0.84 | DDB1 (0.43) | MAPTRAB9ASMN1; SMN2NPC1PIK3CG | |
| SCHEMBL13097414 | 0.82 | PARP1 (0.45) | MAPTRAB9ASMN1; SMN2NPC1MGLL | |
| SCHEMBL13097417 | 0.81 | FFAR1 (0.45) | MAPTRAB9ASMN1; SMN2NPC1MGLL | |
| SCHEMBL13097085 | 0.81 | PRKDC (0.44) | MAPTRAB9ASMN1; SMN2NPC1PIK3CG | |
| SCHEMBL13097421 | 0.80 | FFAR1 (0.44) | MAPTRAB9ASMN1; SMN2NPC1MGLL | |
| SCHEMBL13096970 | 0.79 | MAOB (0.51) | MAPTRAB9ASMN1; SMN2NPC1BCHE | |
| SCHEMBL13097081 | 0.79 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2NPC1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | MAPT 4661/4885PIK3CD 704/4885RAB9A 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.