SCHEMBL130980

SCHEMBL130980

CC(=O)O[Si](C)(C)O[Si](C)(C)OC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1638894 0.97 ALDH1A1 (0.35) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL10795711 0.97 ALDH1A1 (0.35) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL5559882 0.89 HSD17B10 (0.31) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL1087580 0.89 HSD17B10 (0.31) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL1087490 0.89 HSD17B10 (0.31) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL1087360 0.89 HSD17B10 (0.31) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL1051766 0.88 ALDH1A1 (0.33) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL30592944 0.87
SCHEMBL74717 0.87 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL203462 0.86 HSD17B10 (0.32) ALDH1A1TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608716-B8 PROCESS FOR THE PREPARATION OF POLY(SILYL ESTER)S, AND THEIR USES PPG BV (NL) 2012-03-07 EP claimed
EP-1608716-B1 PROCESS FOR THE PREPARATION OF POLY(SILYL ESTER)S, AND THEIR USES SIGMAKALON B V (NL) 2011-11-16 EP claimed
US-20110263605-A1 Azabicyclo[2.2.1]Heptane Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands BRISTOL-MYERS SQUIBB COMPANY 2011-10-27 US claimed
US-7902313-B2 Process for the preparation of poly(silyl ester)s, and their uses SIGMAKALON B.V. (NL) 2011-03-08 US claimed
US-20060241240-A1 Process for the preparation of poly(silyl ester)s, and their uses SIGMA KALON B.V. (NL) 2006-10-26 US claimed
JP-2006521438-A 2006-09-21 JP claimed
EP-1608716-A1 PROCESS FOR THE PREPARATION OF POLY(SILYL ESTER)S, AND THEIR USES SigmaKalon B.V. (NL) 2005-12-28 EP claimed
WO-2004085560-A1 PROCESS FOR THE PREPARATION OF POLY(SILYL ESTER)S, AND THEIR USES SIGMAKALON B.V. (NL) 2004-10-07 WO claimed
US-20240368427-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, OPTICAL COMPONENT, AND COMPOSITE MEMBER JNC CORPORATION (JP) 2024-11-07 US disclosed
EP-4386053-A2 SILOXANE POLYMER COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, OPTICAL COMPONENT, AND COMPOSITE MEMBER JNC Corporation (JP) 2024-06-19 EP disclosed
CN-117795010-A Silicone polymer composition, cured product, electronic component, optical component, and composite member 捷恩智株式会社 2024-03-29 CN disclosed
WO-2022215759-A2 SILOXANE POLYMER COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, OPTICAL COMPONENT, AND COMPOSITE MEMBER JNC株式会社 2022-10-13 WO disclosed
EP-1719794-B1 NOVEL POLYMERS AND USES THEREOF MITSUI CHEMICALS INC (JP) 2017-01-04 EP disclosed
CN-101817929-B Novel polymers and uses thereof MITSUI CHEMICALS INC 2012-08-22 CN disclosed
CN-1914253-A Novel polymers and uses thereof MITSUI CHEMICALS INC (JP) 2007-02-14 CN disclosed
EP-1719794-A1 NOVEL POLYMERS AND USES THEREOF Mitsui Takeda Chemicals, Inc. (JP) 2006-11-08 EP disclosed
EP-0205932-B1 PROCESS FOR PREPARING ORGANOPOLYSILOXANES CONTAINING ACETOXY GROUPS OR HALOGEN ATOMS WHICH ARE LINKED DIRECTLY TO SILICON Wacker-Chemie GmbH (DE) 1989-11-15 EP disclosed
US-4680365-A Method for preparing acetoxysiloxanes and organo(poly)siloxanes having halogen bonded to silicon WACKER-CHEMIE GMBH (DE) 1987-07-14 US disclosed
US-4678468-A HEPARIN IN INTERPENETRATING POLYMER NETWORK BIO-MEDICAL CO., LTD. (JP) 1987-07-07 US disclosed
EP-0205932-A1 Process for preparing organopolysiloxanes containing acetoxy groups or halogen atoms which are linked directly to silicon Wacker-Chemie GmbH (DE) 1986-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263605-A1 Azabicyclo[2.2.1]Heptane Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands CHRNA7, CHRNA2, CHRNA5 ALDH1A1 531/4885TSHR 329/4885HSD17B10 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.