Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.69 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.65 |
| ▸ | PTGES | O14684 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | NT5E | P21589 | 2/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374214 | 1.00 | CA9 (0.69) | CA9SLC10A1PTGESCA1CA2 | |
| SCHEMBL5454212 | 0.92 | CA9 (0.58) | CA9SLC10A1PTGESCA1CA2 | |
| SCHEMBL5454208 | 0.92 | CA9 (0.58) | CA9SLC10A1PTGESCA1CA2 | |
| SCHEMBL13293181 | 0.88 | PTPN1 (0.68) | CA9SLC10A1CA1CA2NT5E | |
| SCHEMBL5448725 | 0.88 | PTPN1 (0.68) | CA9SLC10A1CA1CA2NT5E | |
| SCHEMBL13098042 | 0.88 | PTPN1 (0.68) | CA9SLC10A1CA1CA2NT5E | |
| SCHEMBL14374360 | 0.88 | PTPN1 (0.56) | CA9SLC10A1PTGESCA1CA2 | |
| SCHEMBL5452790 | 0.88 | CA9 (0.55) | CA9SLC10A1PTGESCA1CA2 | |
| SCHEMBL5444226 | 0.87 | CA9 (0.54) | CA9SLC10A1PTGESCA1CA2 | |
| Betulin Diacetate SCHEMBL10523254 | 0.86 | SLC10A1 (0.85) | CA9SLC10A1PTGESCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273801-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | Valition teknillinen tutikimuskeskus (FI) | 2010-10-28 | — | — | US | disclosed |
| US-20100273801-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | Valition teknillinen tutikimuskeskus (FI) | 2010-10-28 | — | — | US | disclosed |
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-08-05 | — | — | US | disclosed |
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-08-05 | — | — | US | disclosed |
| US-20100190795-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-07-29 | — | — | US | disclosed |
| US-20100190795-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-07-29 | — | — | US | disclosed |
| WO-2007141389-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007141391-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | BET1, PGGT1B, RABGGTB | CA9 451/4885SLC10A1 2832/4885PTGES 610/4885 |
| US-20100273801-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | BET1, CUTA, BECN1 | CA9 3167/4885SLC10A1 2928/4885PTGES 947/4885 |
| US-20100190795-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | BET1, BECN1, PGGT1B | CA9 4612/4885SLC10A1 3369/4885PTGES 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.