Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29775933 | 0.81 | CYP2A6 (0.58) | RPS6KA3KDM4EERN1ALDH1A1CYP1A2 | |
| SCHEMBL23775013 | 0.81 | CYP2A6 (0.58) | RPS6KA3KDM4EERN1ALDH1A1CYP1A2 | |
| SCHEMBL2283975 | 0.79 | — | — | |
| SCHEMBL7086650 | 0.78 | EP300 (0.44) | RPS6KA3KDM4EMAPKAPK2EP300KAT2B | |
| Bromide SCHEMBL20854689 | 0.77 | — | — | |
| SCHEMBL22236422 | 0.77 | RPS6KA3 (0.50) | RPS6KA3KDM4EMAPKAPK2EP300KAT2B | |
| SCHEMBL11886365 | 0.76 | CYP2A6 (0.48) | KDM4EMAOAMAOBALDH1A1CYP1A2 | |
| SCHEMBL31627406 | 0.75 | CSNK1A1 (0.42) | RPS6KA3KDM4EIDO1ALDH1A1CYP1A2 | |
| SCHEMBL11886375 | 0.73 | RPS6KA3 (0.35) | RPS6KA3KDM4EMAPKAPK2EP300KAT2B | |
| SCHEMBL26104342 | 0.73 | CYP17A1 (0.48) | MAOAMAOBIDO1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100270537-A1 | OPTOELECTRONIC DEVICES AND ORGANIC COMPOUNDS USED THEREIN | GENERAL ELECTRIC COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100270537-A1 | OPTOELECTRONIC DEVICES AND ORGANIC COMPOUNDS USED THEREIN | GENERAL ELECTRIC COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100270537-A1 | OPTOELECTRONIC DEVICES AND ORGANIC COMPOUNDS USED THEREIN | AOC3, C3AR1, AOC2 | RPS6KA3 1040/4885KDM4E 4692/4885MAPKAPK2 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.