SCHEMBL13098671

SCHEMBL13098671

CNC(=O)N(CCCCCCN(C(=O)NC)C(C)C)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.37
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
KDM4C Q9H3R0 2/20 0.30
KDM4A O75164 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23717869 0.88 EPHX2 (0.39) EPHX2MEN1KMT2AKDM4CKDM4A
SCHEMBL19027652 0.78 NAMPT (0.40) MEN1KMT2A
SCHEMBL967025 0.77 MEN1 (0.33) MEN1KMT2A
SCHEMBL19027666 0.76 CA1 (0.37) MEN1KMT2A
SCHEMBL4373921 0.72 MEN1 (0.47) EPHX2MEN1KMT2AKDM4C
SCHEMBL21121282 0.70 EPHX2 (0.38) EPHX2KDM4CKDM4APHF8KDM2A
SCHEMBL3983529 0.69 MEN1 (0.44) EPHX2MEN1KMT2AKDM4C
SCHEMBL1759008 0.68 EPHX2 (0.54) EPHX2MEN1KMT2ATSHR
SCHEMBL23420687 0.68 ZDHHC20 (0.41) EPHX2BCHEACHETSHR
SCHEMBL12512504 0.68 EPHX2 (0.50) EPHX2MEN1KMT2AKDM4CPHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100273008-A1 POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS SIKA TECHNOLOGY AG (CH) 2010-10-28 US disclosed