Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.35 |
| ▸ | KDM5A | P29375 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13098671 | 0.88 | EPHX2 (0.37) | EPHX2KDM4CKDM4AMEN1KMT2A | |
| SCHEMBL3983529 | 0.82 | MEN1 (0.44) | EPHX2CA12CA1CA9KDM4C | |
| SCHEMBL967025 | 0.79 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL4373921 | 0.77 | MEN1 (0.47) | EPHX2KDM4CKDM5AMEN1FAAH | |
| SCHEMBL1758802 | 0.77 | EPHX2 (0.45) | EPHX2CA12CA1CA9MMP1 | |
| SCHEMBL498398 | 0.77 | EPHX2 (0.41) | EPHX2CA12CA1CA9KDM4C | |
| SCHEMBL20780283 | 0.76 | EPHX2 (0.39) | EPHX2CA12CA1CA9MMP1 | |
| SCHEMBL8147042 | 0.75 | EPHX2 (0.41) | EPHX2CA12CA1CA9MMP1 | |
| SCHEMBL5300087 | 0.75 | EPHX2 (0.41) | EPHX2CA12CA1CA9MMP1 | |
| SCHEMBL31093174 | 0.75 | EPHX2 (0.47) | EPHX2CA12CA1CA9KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078164-B1 | PTEN binding compounds, formulations, and uses thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078164-B1 | PTEN binding compounds, formulations, and uses thereof | PTEN, EYA2, PIK3CA | EPHX2 4690/4885CA12 4549/4885CA1 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.