Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 7/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479006 | 1.00 | JAK2 (0.39) | JAK2BTKLPLLIPGIDO1 | |
| SCHEMBL29388148 | 0.89 | IDO1 (0.46) | JAK2BTKLPLLIPGIDO1 | |
| SCHEMBL15586496 | 0.89 | IDO1 (0.46) | JAK2BTKLPLLIPGIDO1 | |
| SCHEMBL13527502 | 0.89 | LPL (0.44) | JAK2BTKLPLLIPGCA1 | |
| SCHEMBL31170540 | 0.81 | JAK2 (0.35) | JAK2BTKLPLLIPGCYP1A2 | |
| SCHEMBL333869 | 0.81 | LPL (0.46) | JAK2BTKLPLLIPGHPGD | |
| SCHEMBL2027186 | 0.81 | LPL (0.48) | JAK2BTKLPLLIPGCA1 | |
| SCHEMBL3203922 | 0.80 | JAK2 (0.42) | JAK2BTKLPLLIPGCA1 | |
| SCHEMBL15073956 | 0.80 | LPL (0.38) | JAK2BTKLPLLIPG | |
| SCHEMBL17322311 | 0.80 | CYP1A2 (0.48) | JAK2BTKLPLLIPGCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. | 2024-02-22 | — | — | US | disclosed |
| US-8957407-B2 | Anthracene derivatives, preparation method thereof and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2015-02-17 | — | — | US | disclosed |
| US-8957407-B2 | Anthracene derivatives, preparation method thereof and organic light emitting diode using the same | LG CHEM, LTD. (KR) | 2015-02-17 | — | — | US | disclosed |
| US-20100252817-A1 | New Anthracene Derivatives, Preparation Method Thereof and Organic Light Emitting Diode Using the Same | LG CHEM. LTD. (KR) | 2010-10-07 | — | — | US | disclosed |
| US-20100252817-A1 | New Anthracene Derivatives, Preparation Method Thereof and Organic Light Emitting Diode Using the Same | LG CHEM. LTD. (KR) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100252817-A1 | New Anthracene Derivatives, Preparation Method Thereof and Organic Light Emitting Diode Using the Same | CYBA, XPOT, TOMM22 | JAK2 2532/4885BTK 1809/4885LPL 3685/4885 |
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | KRAS, HRAS, APC | JAK2 1651/4885BTK 3193/4885LPL 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.