Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.34 |
| ▸ | CA1 | P00915 | 7/20 | 0.34 |
| ▸ | CA2 | P00918 | 7/20 | 0.34 |
| ▸ | CA4 | P22748 | 6/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100299 | 0.96 | CA12 (0.35) | CA12CA1CA2CA4PTGS2 | |
| SCHEMBL13100318 | 0.95 | CA12 (0.34) | CA12CA1CA2CA4PTGS2 | |
| SCHEMBL13100359 | 0.92 | CA1 (0.39) | CA12CA1CA2CA4PTGS2 | |
| SCHEMBL13100297 | 0.91 | KMT2A (0.34) | CA12CA1CA2CA4PTGS2 | |
| SCHEMBL13099735 | 0.91 | CYP1A2 (0.35) | CA1CA2PTGS2EGFRCSF1R | |
| SCHEMBL13099757 | 0.89 | PTGS2 (0.35) | CA1CA2PTGS2EGFRCSF1R | |
| SCHEMBL13100370 | 0.89 | CA1 (0.41) | CA12CA1CA2CA4PTGS2 | |
| SCHEMBL13100358 | 0.88 | CA1 (0.38) | CA12CA1CA2CA4PTGS2 | |
| SCHEMBL13100282 | 0.88 | CA1 (0.40) | CA12CA1CA2CA4PTGS2 | |
| SCHEMBL13100361 | 0.87 | CA1 (0.39) | CA12CA1CA2CA4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256357-A1 | HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE | AGOURON PHARMACEUTICALS, INC. | 2010-10-07 | — | — | US | disclosed |
| US-20100256357-A1 | HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE | AGOURON PHARMACEUTICALS, INC. | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256357-A1 | HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE | CA2, CA7, CA9 | CA12 8/4885CA1 7/4885CA2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.