Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CLPP | Q16740 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29883119 | 0.84 | KMT2A (0.63) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL1038680 | 0.84 | KMT2A (0.63) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL30474239 | 0.83 | KMT2A (0.61) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL16220609 | 0.83 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL12706737 | 0.83 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL5777297 | 0.83 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL2907160 | 0.82 | KMT2A (0.57) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL17984056 | 0.82 | KMT2A (0.60) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL5776313 | 0.81 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL5776892 | 0.81 | MEN1 (0.59) | MEN1KMT2ANPC1RAB9ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100266504-A1 | CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266504-A1 | CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF | HTR2C, HTR5A, HTR3C | MEN1 4418/4885KMT2A 3157/4885NPC1 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.