Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.72 |
| ▸ | ACHE | P22303 | 6/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100739 | 1.00 | ABCG2 (0.72) | ABCG2ACHECYP19A1MAPTCYP1A1 | |
| SCHEMBL13100738 | 1.00 | ABCG2 (0.72) | ABCG2ACHECYP19A1MAPTCYP1A1 | |
| SCHEMBL23356493 | 0.90 | CYP1A1 (0.74) | ABCG2ACHECYP19A1MAPTCYP1A1 | |
| SCHEMBL12978383 | 0.89 | ABCG2 (0.68) | ABCG2ACHECYP19A1MAPTCYP1A1 | |
| SCHEMBL7663826 | 0.88 | ACHE (0.70) | ACHECYP19A1MAPTCYP1A1CYP1A2 | |
| SCHEMBL7671518 | 0.88 | ACHE (0.70) | ACHECYP19A1MAPTCYP1A1CYP1A2 | |
| SCHEMBL25134990 | 0.87 | ACHE (0.58) | ABCG2ACHECYP19A1MAPTCYP1A1 | |
| SCHEMBL13091033 | 0.85 | ABCG2 (0.73) | ABCG2ACHECYP19A1MAPTCYP1A1 | |
| SCHEMBL13091031 | 0.85 | ABCG2 (0.73) | ABCG2ACHECYP19A1MAPTCYP1A1 | |
| SCHEMBL13091029 | 0.85 | ABCG2 (0.73) | ABCG2ACHECYP19A1MAPTCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399691-B2 | Method for resolution of a mixture of pinocembrin optical isomers, especially a pinocembrin racemate | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO. LTD. (CN) | 2013-03-19 | — | — | US | disclosed |
| US-20100261916-A1 | METHOD FOR RESOLUTION OF A MIXTURE OF PINOCEMBRIN OPTICAL ISOMERS, ESPECIALLY A PINOCEMBRIN RACEMATE | CSPC Zhonggi Pharmaceutical Technology (Shijiazhuang) Co. Ltd. (CN) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261916-A1 | METHOD FOR RESOLUTION OF A MIXTURE OF PINOCEMBRIN OPTICAL ISOMERS, ESPECIALLY A PINOCEMBRIN RACEMATE | SPR, NISCH, PNN | ABCG2 334/4885ACHE 2771/4885CYP19A1 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.