Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753490 | 0.95 | HTR1A (0.40) | HTR1APRMT1FOLR1TLR2MAPT | |
| SCHEMBL13100803 | 0.94 | PRMT1 (0.42) | HTR1APRMT1FOLR1TLR2MAPT | |
| SCHEMBL4753277 | 0.94 | HTR1A (0.45) | HTR1APRMT1FOLR1MAPTMEN1 | |
| SCHEMBL4753486 | 0.94 | HTR1A (0.41) | HTR1APRMT1FOLR1TLR2MAPT | |
| SCHEMBL4753262 | 0.88 | HTR1A (0.44) | HTR1APRMT1FOLR1PTPN1FOLH1 | |
| SCHEMBL4753430 | 0.88 | HTR1A (0.46) | HTR1APRMT1FOLR1PTPN1FOLH1 | |
| SCHEMBL276744 | 0.87 | HTR1A (0.46) | HTR1APRMT1FOLR1PTPN1FOLH1 | |
| SCHEMBL13100832 | 0.87 | PRMT1 (0.42) | HTR1APRMT1FOLR1TLR2MAPT | |
| SCHEMBL4753382 | 0.86 | HTR1A (0.41) | HTR1APRMT1FOLR1TLR2MAPT | |
| SCHEMBL13100804 | 0.86 | PRMT1 (0.38) | HTR1APRMT1FOLR1TLR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100274023-A1 | NOVEL INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MESO-SUBSTITUTED CYANINE, MEROCYANINE AND OXONOLE DYES | AGFA GRAPHICS NV (BE) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274023-A1 | NOVEL INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF MESO-SUBSTITUTED CYANINE, MEROCYANINE AND OXONOLE DYES | MB, MYADM, PYCR1 | HTR1A 3200/4885PRMT1 418/4885FOLR1 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.