SCHEMBL13101262

SCHEMBL13101262

C=CCC(C(=C)OCC)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.35
GRIK1 P39086 2/20 0.35
GRIK2 Q13002 2/20 0.35
ALDH1A1 P00352 6/20 0.34
CYP2C19 P33261 1/20 0.34
CPA1 P15085 1/20 0.34
TSHR P16473 3/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32
MAPT P10636 1/20 0.32
CYP2D6 P10635 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1564401 0.84 CPA1 (0.40) HCAR2GRIK1GRIK2ALDH1A1CYP2C19
SCHEMBL793641 0.79 ALDH1A1 (0.40) HCAR2ALDH1A1CPA1TSHRLMNA
Ethyl Acetate SCHEMBL28822004 0.78 ALDH1A1 (0.50) HCAR2GRIK1GRIK2ALDH1A1CYP2C19
Butane SCHEMBL18797012 0.76 TSHR (0.39) HCAR2ALDH1A1TSHRLMNAHSD17B10
Acetic Acid SCHEMBL28822001 0.76 MMP8 (0.37) HCAR2ALDH1A1CYP2C19CPA1TSHR
SCHEMBL13101256 0.75 TDP1 (0.33) HCAR2ALDH1A1TSHRLMNASMN1; SMN2
SCHEMBL11736110 0.74 GRIK1 (0.36) GRIK1GRIK2ALDH1A1CYP2C19CPA1
SCHEMBL3607061 0.74 ALDH1A1 (0.39) HCAR2ALDH1A1CYP2C19TSHRLMNA
SCHEMBL31636 0.73 GRIK1 (0.48) GRIK1GRIK2ALDH1A1CYP2C19CPA1
SCHEMBL19284346 0.73 SOAT1 (0.37) HCAR2ALDH1A1CPA1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100273931-A1 DECARBOXYLATING BLOCK COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-28 US disclosed