Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102262 | 0.94 | CYP3A4 (0.42) | ALDH1A1LMNACYP3A4CSNK1DHTT | |
| SCHEMBL13101694 | 0.91 | ALDH1A1 (0.44) | ALDH1A1LMNACYP3A4CSNK1DHTT | |
| SCHEMBL13101727 | 0.89 | CSNK1D (0.41) | ALDH1A1LMNACYP3A4CSNK1DHTT | |
| SCHEMBL13101676 | 0.89 | ALDH1A1 (0.42) | ALDH1A1LMNACSNK1DHTTGPR139 | |
| SCHEMBL3067313 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNACYP3A4CSNK1DHTT | |
| SCHEMBL13102276 | 0.87 | TRPV4 (0.44) | ALDH1A1LMNACYP3A4CSNK1DHTT | |
| SCHEMBL13102008 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNACSNK1DHTTMEN1 | |
| SCHEMBL13102103 | 0.86 | HDAC1 (0.42) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL13102318 | 0.85 | SLC2A1 (0.45) | ALDH1A1LMNACSNK1DHTTGPR139 | |
| SCHEMBL13101997 | 0.85 | HDAC1 (0.45) | ALDH1A1LMNACYP3A4HTTGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329713-B2 | Fused ring heterocycles as potassium channel modulators | ICAGEN INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100273784-A1 | FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273784-A1 | FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | KCNK17, KCNJ2, KCNJ1 | ALDH1A1 2354/4885LMNA 1121/4885CYP3A4 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.