Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.38 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13101676 | 0.94 | ALDH1A1 (0.42) | ALDH1A1HTTCSNK1DGPR139LMNA | |
| SCHEMBL13102190 | 0.92 | CSNK1D (0.41) | ALDH1A1HTTCSNK1DGPR139LMNA | |
| SCHEMBL13102465 | 0.91 | ALDH1A1 (0.51) | ALDH1A1HTTGPR139LMNAMEN1 | |
| SCHEMBL13102277 | 0.90 | ALDH1A1 (0.44) | ALDH1A1HTTCSNK1DGPR139LMNA | |
| SCHEMBL13102262 | 0.89 | CYP3A4 (0.42) | ALDH1A1HTTCSNK1DGPR139LMNA | |
| SCHEMBL13102264 | 0.88 | ALDH1A1 (0.46) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL13101701 | 0.88 | LMNA (0.39) | ALDH1A1HTTGPR139LMNASLC2A1 | |
| SCHEMBL13101951 | 0.87 | IDO1 (0.47) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL13101986 | 0.87 | ALDH1A1 (0.44) | ALDH1A1HTTCSNK1DGPR139LMNA | |
| SCHEMBL13102318 | 0.87 | SLC2A1 (0.45) | ALDH1A1HTTCSNK1DGPR139LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329713-B2 | Fused ring heterocycles as potassium channel modulators | ICAGEN INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100273784-A1 | FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273784-A1 | FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | KCNK17, KCNJ2, KCNJ1 | ALDH1A1 2354/4885HTT 329/4885CSNK1D 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.