SCHEMBL13104366

SCHEMBL13104366

COc1ccc(NC(=O)Nc2ccc(C)c(NC(=O)Oc3ccccc3)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 8/20 0.60
HTT P42858 3/20 0.60
GAA P10253 2/20 0.60
ALDH1A1 P00352 2/20 0.60
MAPT P10636 9/20 0.60
TP53 P04637 2/20 0.58
TSHR P16473 1/20 0.58
NPC1 O15118 7/20 0.54
RAB9A P51151 7/20 0.54
PKM P14618 4/20 0.54
POLB P06746 2/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPK1 P28482 1/20 0.52
IGF1R P08069 1/20 0.52
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
KCNJ6 P48051 1/20 0.51
KCNJ5 P48544 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13104370 0.98 SMN1; SMN2 (0.64) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL13104373 0.96 SMN1; SMN2 (0.63) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL13104359 0.92 MAPT (0.55) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL13104381 0.92 MAPT (0.54) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL1396095 0.90 MAPT (0.52) HTTGAAALDH1A1MAPTTP53
SCHEMBL13104406 0.90 MAPT (0.58) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL13104367 0.89 ALDH1A1 (0.51) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL13415474 0.89 MAPT (0.52) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL13104363 0.89 MAPT (0.57) SMN1; SMN2HTTGAAALDH1A1MAPT
SCHEMBL13593024 0.87 MAPT (0.57) SMN1; SMN2HTTGAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807738-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2010-10-05 US disclosed
US-7807738-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2010-10-05 US disclosed
US-20100105941-A1 NOVEL COMPOUND FOR COLOR-PRODUCING COMPOSITION, AND RECORDING MATERIAL KABASHIMA KAZUO 2010-04-29 US disclosed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US disclosed
US-7635662-B2 Compound for color-producing composition, and recording material CHEMIPRO KASEI KAISHA, LTD. (JP) 2009-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105941-A1 NOVEL COMPOUND FOR COLOR-PRODUCING COMPOSITION, AND RECORDING MATERIAL UMPS, UROD, UGP2 SMN1; SMN2 2351/4885HTT 3102/4885GAA 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.