SCHEMBL1310574

SCHEMBL1310574

Cc1ccc(NC(=S)Nc2ccc(O)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.78
ALDH1A1 P00352 5/20 0.78
MAPT P10636 4/20 0.78
KDM4E B2RXH2 2/20 0.78
THRB P10828 2/20 0.78
L3MBTL1 Q9Y468 2/20 0.78
KMT2A Q03164 3/20 0.68
MEN1 O00255 2/20 0.68
CYP1A2 P05177 2/20 0.68
CYP3A4 P08684 2/20 0.68
CYP2C19 P33261 2/20 0.68
HTT P42858 1/20 0.68
LMNA P02545 2/20 0.67
MAOA P21397 1/20 0.67
MAOB P27338 1/20 0.67
RRM1 P23921 1/20 0.63
RRM2 P31350 1/20 0.63
RRM2B Q7LG56 1/20 0.63
NPSR1 Q6W5P4 1/20 0.61
TDP1 Q9NUW8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276739 0.91 KMT2A (0.79) GAAALDH1A1MAPTKDM4ETHRB
SCHEMBL5451731 0.83 ALDH1A1 (0.74) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL25943052 0.81 GAA (0.65) GAAALDH1A1MAPTKDM4ETHRB
SCHEMBL1747930 0.81 KMT2A (0.66) GAAALDH1A1MAPTKDM4ETHRB
SCHEMBL11074089 0.81 HTT (0.66) GAAALDH1A1MAPTKDM4EKMT2A
SCHEMBL2235398 0.80 GAA (1.00) GAAALDH1A1MAPTKDM4ETHRB
SCHEMBL1882197 0.80 CYP1A2 (0.70) GAAALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL2590098 0.80 CYP1A2 (0.64) GAAALDH1A1MAPTL3MBTL1KMT2A
SCHEMBL5078028 0.80 ALDH1A1 (0.74) GAAALDH1A1MAPTKDM4ETHRB
SCHEMBL27920271 0.79 GAA (0.62) GAAALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101762982-B Infrared positive thermal-sensitive offset plate CHENGDU XINGRAPHICS CO LTD 2013-03-13 CN disclosed
CN-101762972-B Infrared positive thermal-sensitive imaging composition CHENGDU XINGRAPHICS CO LTD 2012-12-26 CN disclosed
US-20110271859-A1 THERMOSENSITIVE IMAGING COMPOSITION AND LITHOGRAPHIC PLATE COMPRISING THE SAME CHENGDU XINGRAPHICS CO., LTD. (CN) 2011-11-10 US disclosed
EP-2380062-A1 THERMOSENSITIVE IMAGING COMPOSITION AND LITHOGRAPHIC PLATE COMPRISING THE SAME Chengdu Xingraphics Co., Ltd. (CN) 2011-10-26 EP disclosed
WO-2010072157-A1 THERMOSENSITIVE IMAGING COMPOSITION AND LITHOGRAPHIC PLATE COMPRISING THE SAME CHENGDU XINGRAPHICS CO., LTD. (CN) 2010-07-01 WO disclosed
CN-101762972-A Infrared positive thermal-sensitive imaging composition CHENGDU XINGRAPHICS CO LTD 2010-06-30 CN disclosed
CN-101762982-A Infrared positive thermal-sensitive offset plate CHENGDU XINGRAPHICS CO LTD 2010-06-30 CN disclosed