SCHEMBL2235398

SCHEMBL2235398

Oc1ccc(NC(=S)Nc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 1.00
KMT2A Q03164 5/20 1.00
MAOA P21397 3/20 1.00
MAOB P27338 3/20 1.00
LMNA P02545 2/20 1.00
ALDH1A1 P00352 6/20 0.82
MAPT P10636 4/20 0.82
KDM4E B2RXH2 1/20 0.82
THRB P10828 1/20 0.82
L3MBTL1 Q9Y468 1/20 0.82
CYP3A4 P08684 1/20 0.77
TAS2R38 P59533 1/20 0.77
HSD17B10 Q99714 1/20 0.77
RAB9A P51151 3/20 0.71
MEN1 O00255 3/20 0.71
NOX1 Q9Y5S8 3/20 0.71
NPC1 O15118 2/20 0.71
CYP1A2 P05177 1/20 0.60
CYP2C19 P33261 1/20 0.60
IDO1 P14902 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956322 0.91 ALDH1A1 (0.94) GAAKMT2AMAOAMAOBLMNA
SCHEMBL132620 0.88 ALDH1A1 (1.00) GAAKMT2AMAOAMAOBLMNA
SCHEMBL11309040 0.88 GAA (0.78) GAAKMT2AMAOAMAOBLMNA
SCHEMBL11318231 0.88 GAA (0.78) GAAKMT2AMAOAMAOBLMNA
SCHEMBL9470190 0.85 ALDH1A1 (0.94) GAAKMT2AMAOAMAOBLMNA
SCHEMBL9243020 0.84 ALDH1A1 (0.81) GAAKMT2AMAOAMAOBLMNA
Thiourea SCHEMBL21055683 0.81 ALDH1A1 (0.85) GAAKMT2AMAOAMAOBLMNA
SCHEMBL29726315 0.81 KMT2A (1.00) GAAKMT2AMAOAMAOBLMNA
SCHEMBL5455313 0.81 KMT2A (1.00) GAAKMT2AMAOAMAOBLMNA
SCHEMBL5081276 0.80 NOX1 (0.85) GAAKMT2AMAOAMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5236633-A Blend of transparent polymer, thiourea and copper compounds JUJO PAPER CO., LTD. (JP) 1993-08-17 US claimed
US-4264710-A AN ETHYLENICALLY UNSATURATED COMPOUND, AND A PHOTOPOLYMERIZATION INIATOR FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US claimed
EP-3586025-B1 SELF-ENERGIZING ELECTROMAGNETIC DISCONNECT ACTUATOR LINAMAR CORP (CA) 2026-04-08 EP disclosed
EP-3516252-B1 INTEGRATED DISCONNECTING TWIN CLUTCH SYSTEM AND DUAL ACTION PISTON LINAMAR CORP (CA) 2025-04-09 EP disclosed
EP-3221175-B1 CONTROL SYSTEM AND METHOD OF CONTROLLING A DRIVELINE JAGUAR LAND ROVER LTD (GB) 2024-04-17 EP disclosed
EP-3221174-B1 CONTROL SYSTEM AND METHOD OF CONTROLLING A DRIVELINE JAGUAR LAND ROVER LTD (GB) 2024-01-10 EP disclosed
EP-3978781-B1 MULTI SPEED TRANSMISSION LINAMAR CORP (CA) 2023-11-01 EP disclosed
CN-109390350-B Semiconductor memory device of three-dimensional structure 爱思开海力士有限公司 2023-08-22 CN disclosed
CN-110341468-B Control system and method for controlling a drive train 捷豹路虎有限公司 2022-08-19 CN disclosed
US-11365770-B2 Self-energizing electromagnetic disconnect actuator LINAMAR CORPORATION (CA) 2022-06-21 US disclosed
EP-3519718-B1 MULTI SPEED TRANSMISSION LINAMAR CORP (CA) 2022-05-04 EP disclosed
CN-1315936-C Flame-resistant vinyl chloride based resin composition and formed product therefrom MITSUBISHI PLASTICS INC (JP) 2007-05-16 CN disclosed
US-20060014874-A1 Flame-resistant vinyl chlorride based resin composition and formed product therefrom MITSUBISHI PLASTICS, INC. (JP) 2006-01-19 US disclosed
CN-1708550-A Flame-resistant vinyl chloride based resin composition and formed product therefrom MITSUBISHI PLASTICS INC (JP) 2005-12-14 CN disclosed
US-20050223629-A1 Method of inhibiting deposit formation in a jet fuel at high temperatures INFINEUM INTERNATIONAL LIMITED (GB) 2005-10-13 US disclosed
EP-1533359-A1 A method of inhibiting deposit formation in a jet fuel at high temperature Infineum International Limited (GB) 2005-05-25 EP disclosed
CN-1054803-C Polycarbonic acid ester resin layered products absorbing near-infrared and formed products made of same DAICEL CHEM (JP) 2000-07-26 CN disclosed
US-5393443-A Hard-coating, heat-absorbing composition and heat-shielding substance JUJO PAPER CO., LTD. (JP) 1995-02-28 US disclosed
CN-1094354-A Polycarbonate-based resin laminate of absorption near infrared ray and formed body thereof DAICEL CHEM (JP) 1994-11-02 CN disclosed
US-4048333-A Method for treating a picorna virus infection MEDIZINSKA AKADEMIA (BG) 1977-09-13 US disclosed