Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106872 | 0.83 | KDM4E (0.52) | ROCK2ROCK1 | |
| SCHEMBL13106900 | 0.77 | ROCK2 (0.55) | ROCK2ROCK1CCR2 | |
| SCHEMBL3312172 | 0.76 | ROCK2 (0.53) | ROCK2ROCK1ITKCCR2 | |
| SCHEMBL3313228 | 0.76 | ROCK2 (0.53) | ROCK2ROCK1ITKCCR2 | |
| SCHEMBL14077547 | 0.75 | KDM4E (0.50) | — | |
| SCHEMBL13122256 | 0.75 | ROCK2 (0.84) | ROCK2ROCK1CCR2 | |
| SCHEMBL5413101 | 0.74 | KDM4E (0.49) | — | |
| SCHEMBL14077546 | 0.74 | KDM4E (0.49) | — | |
| SCHEMBL5408219 | 0.74 | ROCK2 (0.59) | ROCK2ROCK1ITKCCR2 | |
| SCHEMBL14824601 | 0.73 | ROCK2 (0.49) | ROCK2ROCK1CAMK2DITKCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812045-B2 | Antifungal triazole derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-10-12 | — | — | US | disclosed |
| US-20080194661-A1 | Antifungal Triazole Derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194661-A1 | Antifungal Triazole Derivatives | ERG28, CYP51A1, CYP3A43 | ROCK2 3079/4885ROCK1 3410/4885CAMK2D 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.