Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3451760 | 0.99 | NPSR1 (0.51) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| SCHEMBL13109492 | 0.95 | NPSR1 (0.51) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3451495 | 0.95 | NPSR1 (0.50) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| SCHEMBL13109483 | 0.91 | ITGB3 (0.52) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3453071 | 0.90 | ITGB3 (0.51) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| SCHEMBL3452234 | 0.87 | ITGB3 (0.55) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| SCHEMBL13109491 | 0.84 | ITGB3 (0.53) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3451796 | 0.83 | ITGB3 (0.52) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| SCHEMBL13109489 | 0.82 | ITGB3 (0.54) | NPSR1ITGB3ITGA2BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3452144 | 0.81 | ITGB3 (0.54) | NPSR1ITGB3ITGA2BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |