Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109483 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3453071 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL13109489 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL13109490 | 0.87 | NPSR1 (0.51) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3452144 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL13109492 | 0.86 | NPSR1 (0.51) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3451760 | 0.86 | NPSR1 (0.51) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL13109491 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL13109497 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3451495 | 0.85 | NPSR1 (0.50) | ITGB3ITGA2BMEN1KMT2ACPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | MC5R, MC3R, MC4R | ITGB3 1281/4885ITGA2B 1854/4885MEN1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.