Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 17/20 | 0.82 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | GNA15 | P30679 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450258 | 0.90 | FFAR1 (1.00) | FFAR1PPARGPPARDPPARAFFAR4 | |
| SCHEMBL13110435 | 0.82 | FFAR1 (0.59) | FFAR1PPARGPPARDPPARAFFAR4 | |
| SCHEMBL5638404 | 0.79 | PPARD (0.72) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL10239132 | 0.79 | PPARD (0.60) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL16448791 | 0.78 | FFAR1 (0.75) | FFAR1PPARGPPARDPPARAGNA15 | |
| SCHEMBL1745371 | 0.76 | FFAR1 (0.80) | FFAR1FFAR4 | |
| SCHEMBL5639128 | 0.75 | PPARD (0.79) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL2431256 | 0.75 | ALDH1A1 (0.67) | — | |
| SCHEMBL15211552 | 0.75 | POLB (0.51) | FFAR1PPARDPPARA | |
| SCHEMBL1746739 | 0.75 | FFAR1 (0.69) | FFAR1FFAR4GNA15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |