Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | FABP7 | O15540 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264305 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL29019464 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL27522574 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL17799057 | 0.87 | FABP5 (0.45) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL1311053 | 0.86 | FABP5 (0.44) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL28356620 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL28884667 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL29663619 | 0.84 | FABP5 (0.44) | FABP5FABP7KMT2AEPHX2CYP1A2 | |
| SCHEMBL29019459 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2HIF1AFABP5FABP7KMT2A | |
| SCHEMBL28884665 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2HIF1AFABP5FABP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070157-A1 | REDOX DEHYDRATION COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2017-04-27 | — | — | WO | disclosed |
| WO-2015054337-A1 | HETEROCYCLIC COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2015-04-16 | — | — | WO | disclosed |