Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103972 | 1.00 | CYP3A4 (0.58) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL9102504 | 1.00 | CYP3A4 (0.58) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL9100900 | 0.95 | CYP3A4 (0.54) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL24983638 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL13507373 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL13507904 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL3669026 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL9101384 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL13507688 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPK1ABCB1MEN1KMT2A | |
| SCHEMBL4640426 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPK1ABCB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820835-B2 | Method for producing flavan derivatives | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20090099374-A1 | METHOD FOR PRODUCING FLAVAN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099374-A1 | METHOD FOR PRODUCING FLAVAN DERIVATIVE | ADH5, ADH1C, CYP2E1 | CYP3A4 135/4885MAPK1 3471/4885ABCB1 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.