Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186303 | 0.88 | F10 (0.47) | F10MAPK1HPGDTSHRHRH3 | |
| SCHEMBL10184557 | 0.88 | F10 (0.47) | F10MAPK1HPGDTSHRHRH3 | |
| SCHEMBL10184880 | 0.85 | DGAT1 (0.49) | F10MAPK1HPGDTSHRHRH3 | |
| SCHEMBL10184804 | 0.82 | F10 (0.49) | F10MAPK1HPGDHRH3L3MBTL1 | |
| SCHEMBL13117660 | 0.79 | CCR3 (0.42) | HPGDFAAHEPHX2HRH3KMT2A | |
| SCHEMBL10186309 | 0.77 | F10 (0.42) | F10MAPK1HRH3DGAT1NPC1 | |
| SCHEMBL10185427 | 0.74 | DGAT1 (0.49) | FAAHEPHX2HRH3HSD17B10L3MBTL1 | |
| SCHEMBL13117652 | 0.73 | HSD17B10 (0.38) | FAAHEPHX2HRH3HSD17B10KMT2A | |
| SCHEMBL10186462 | 0.73 | DGAT1 (0.48) | FAAHEPHX2HRH3HSD17B10L3MBTL1 | |
| SCHEMBL10185146 | 0.72 | MAPK1 (0.42) | F10MAPK1HPGDHRH3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |