Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117665 | 0.89 | DGAT1 (0.42) | HSD17B10RAB9ADGAT1HRH3OPRM1 | |
| SCHEMBL13117702 | 0.86 | DGAT1 (0.47) | HSD17B10RAB9ADGAT1HRH3OPRM1 | |
| SCHEMBL13117596 | 0.86 | DGAT1 (0.47) | HSD17B10RAB9ADGAT1HRH3OPRM1 | |
| SCHEMBL13117885 | 0.75 | DGAT1 (0.40) | DGAT1HRH3 | |
| SCHEMBL13117655 | 0.75 | PDE4D (0.39) | DGAT1EPHX2OPRM1MEN1KMT2A | |
| SCHEMBL13117895 | 0.75 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL13117662 | 0.75 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL13117653 | 0.73 | F10 (0.47) | HSD17B10RAB9ADGAT1FAAHEPHX2 | |
| SCHEMBL13117660 | 0.71 | CCR3 (0.42) | DGAT1TRPV1FAAHEPHX2HRH3 | |
| SCHEMBL13117633 | 0.69 | MC4R (0.38) | RAB9AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |