SCHEMBL13117828

SCHEMBL13117828

Cc1c(COc2ccc(Cn3oc(=O)[nH]c3=O)cc2)cccc1-c1ccc(OCCO)c(C)c1C

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 3/20 0.61
▸ PLAT P00750 1/20 0.44
▸ CD274 Q9NZQ7 14/20 0.41
▸ S1PR1 P21453 1/20 0.36
▸ S1PR5 Q9H228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13117899 0.95 FFAR1 (0.61) FFAR1PLATCD274S1PR1S1PR5
SCHEMBL12579009 0.90 FFAR1 (0.66) FFAR1PLATCD274S1PR1S1PR5
SCHEMBL2912862 0.90 FFAR1 (0.50) FFAR1PLATCD274S1PR1S1PR5
SCHEMBL2912159 0.89 FFAR1 (0.63) FFAR1PLATCD274
SCHEMBL12578979 0.89 FFAR1 (0.75) FFAR1PLATCD274S1PR1S1PR5
SCHEMBL2910888 0.87 FFAR1 (0.61) FFAR1PLATCD274
SCHEMBL12578992 0.85 FFAR1 (0.68) FFAR1PLATCD274S1PR1S1PR5
SCHEMBL13117856 0.85 FFAR1 (0.63) FFAR1PLATCD274
SCHEMBL13117903 0.85 FFAR1 (0.60) FFAR1PLATCD274
SCHEMBL2910750 0.84 FFAR1 (0.49) FFAR1PLATCD274S1PR1S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267775-A1 OXADIAZOLIDINEDIONE COMPOUND ASTELLAS PHARMA INC. (JP) 2010-10-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267775-A1 OXADIAZOLIDINEDIONE COMPOUND GPR119, GLP1R, GPR4 FFAR1 38/4885PLAT 3298/4885CD274 1333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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