Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | MANBA | O00462 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | IDUA | P35475 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13105443 | 1.00 | HIF1A (0.35) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL20126411 | 0.87 | — | — | |
| SCHEMBL25633775 | 0.87 | — | — | |
| SCHEMBL25633774 | 0.84 | — | — | |
| SCHEMBL13105442 | 0.82 | HIF1A (0.35) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL13120130 | 0.82 | HIF1A (0.35) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL20009694 | 0.74 | HIF1A (0.39) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL14428823 | 0.71 | HIF1A (0.33) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL13120129 | 0.71 | LMNA (0.38) | LMNA | |
| SCHEMBL13105445 | 0.71 | LMNA (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807418-B2 | Method for producing hybrid polyketide synthases | BIOTICA TECHNOLOGY LIMITED (GB) | 2010-10-05 | — | — | US | disclosed |