Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MANBA | O00462 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20126411 | 0.82 | — | — | |
| SCHEMBL12833579 | 0.77 | HIF1A (0.34) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL10110534 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL18026197 | 0.74 | HIF1A (0.65) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL13120133 | 0.74 | HIF1A (0.35) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL13105443 | 0.74 | HIF1A (0.35) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL14428823 | 0.73 | HIF1A (0.33) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL12750411 | 0.69 | LMNA (0.68) | HIF1AMANBALMNATHRBCYP2C19 | |
| SCHEMBL10035728 | 0.69 | — | — | |
| SCHEMBL17973347 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086793-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086793-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | HIF1A 3889/4885MANBA 1077/4885LMNA 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.