SCHEMBL13120597

SCHEMBL13120597

C=C(CC(=O)CC(C)=O)CC(=O)CC(=O)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.48
▸ KDM6B O15054 1/20 0.48
▸ KDM5C P41229 1/20 0.48
▸ EGLN1 Q9GZT9 1/20 0.48
▸ PHF8 Q9UPP1 1/20 0.48
▸ KDM2A Q9Y2K7 1/20 0.48
▸ LDHA P00338 1/20 0.35
▸ SRR Q9GZT4 1/20 0.35
▸ LMNA P02545 1/20 0.33
▸ SLC15A2 Q16348 1/20 0.33
▸ MGAM O43451 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ SI P14410 1/20 0.32
▸ MGAM2 Q2M2H8 1/20 0.32
▸ ALOX15 P16050 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1774230 0.88 EGLN1 (0.59) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28977856 0.88 EGLN1 (0.59) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL321597 0.85 EGLN1 (0.62) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28887 0.85 EGLN1 (0.62) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28832780 0.83 EGLN1 (0.59) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL12927368 0.80 KDM4E (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28289355 0.78 PHF8 (0.54) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10936077 0.77 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL26967576 0.77 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28078303 0.74 KDM4E (0.50) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807711-B2 Medicinal acidic cannabinoids NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2010-10-05 — — US disclosed
US-20070032544-A1 MEDICINAL ACIDIC CANNABINOIDS NEDERLANDSE ORGANISATIE VOOR TOEGEPASTNATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2007-02-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032544-A1 MEDICINAL ACIDIC CANNABINOIDS CNR2, CNR1, ARFGEF1 KDM4E 2138/4885KDM6B 2729/4885KDM5C 1189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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