Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KDM5C | P41229 | 2/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321597 | 0.92 | EGLN1 (0.62) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL28887 | 0.92 | EGLN1 (0.62) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL1774230 | 0.89 | EGLN1 (0.59) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL28832780 | 0.89 | EGLN1 (0.59) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL28977856 | 0.89 | EGLN1 (0.59) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL28078303 | 0.80 | KDM4E (0.50) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL235434 | 0.80 | KDM4E (0.58) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL3519320 | 0.76 | KDM4E (0.55) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL28706026 | 0.76 | KDM4E (0.55) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL10936077 | 0.76 | KDM4E (0.55) | PHF8KDM2AKDM4EKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263498-B | Sai Nikeweiluo composition and its preparation and application | 妥必徕疗治公司 | 2019-04-26 | — | — | CN | disclosed |