Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SI | P14410 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311993 | 1.00 | POLB (0.47) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL2069140 | 0.84 | HSD17B10 (0.50) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL1312995 | 0.78 | POLB (0.47) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL1311735 | 0.78 | POLB (0.46) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL1312663 | 0.78 | POLB (0.46) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL1312900 | 0.78 | POLB (0.46) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL5790948 | 0.76 | POLB (0.57) | POLBAPAF1HSD17B10ALDH1A1SLC9A1 | |
| SCHEMBL16488274 | 0.76 | SLC9A1 (0.48) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL4221863 | 0.76 | SLC9A1 (0.48) | POLBAPAF1HSD17B10MAPTALDH1A1 | |
| SCHEMBL24422508 | 0.75 | SLC9A1 (0.52) | POLBAPAF1HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387568-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NeuroSearch A/S (DK) | 2011-11-23 | — | — | EP | claimed |
| US-20110275684-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NEUROSEARCH A/S (DK) | 2011-11-10 | — | — | US | claimed |
| US-8040036-B2 | Organic light emitting device and method for manufacturing the same | LG CHEM, LTD. (KR) | 2011-10-18 | — | — | US | claimed |
| WO-2010081898-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NEUROSEARCH A/S (DK) | 2010-07-22 | — | — | WO | claimed |
| US-20110275684-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NEUROSEARCH A/S (DK) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275684-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | GABBR1, ABAT, GABBR2 | POLB 3467/4885APAF1 3265/4885HSD17B10 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.