Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968884 | 1.00 | MEN1 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2SIRT6 | |
| SCHEMBL16622177 | 0.95 | MEN1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2SIRT6 | |
| SCHEMBL23772060 | 0.88 | MEN1 (0.57) | MEN1KMT2ASIRT6SIRT1CASP2 | |
| SCHEMBL24372267 | 0.88 | MEN1 (0.57) | MEN1KMT2ASIRT6SIRT1CASP2 | |
| SCHEMBL18412629 | 0.88 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2SIRT6 | |
| SCHEMBL25968834 | 0.87 | MEN1 (0.48) | MEN1KMT2AALDH1A1RECQL | |
| SCHEMBL16174166 | 0.87 | CASP2 (0.56) | MEN1KMT2ASIRT6SIRT1CASP2 | |
| SCHEMBL19646650 | 0.86 | FOLH1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2SIRT6 | |
| SCHEMBL21964560 | 0.86 | FOLH1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2SIRT6 | |
| SCHEMBL21964558 | 0.86 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019115609-A1 | SACCHARIDE FUNCTIONALISED CARBABORANE CONJUGATES OF HUMAN PEPTIDE Y | UNIVERSITÄT LEIPZIG (DE) | 2019-06-20 | — | — | WO | disclosed |
| US-7820179-B2 | Pegylated PTH as PTH receptor modulators and uses thereof | ELI LILLY AND COMPANY (US) | 2010-10-26 | — | — | US | disclosed |
| US-20090253630-A1 | PEGYLATED PTH AS PTH RECEPTOR MODULATORS AND USES THEREOF | ELI LILLY AND COMPANY | 2009-10-08 | — | — | US | disclosed |
| US-7368427-B1 | GLP-1 analogues | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS (FR) | 2008-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253630-A1 | PEGYLATED PTH AS PTH RECEPTOR MODULATORS AND USES THEREOF | PTH1R, PTMS, CALCR | MEN1 725/4885KMT2A 4622/4885ALDH1A1 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.