SCHEMBL13129307

SCHEMBL13129307

c1ccc(-c2ccc3sc4c(-c5ccccc5)cc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 2/20 0.49
PIM3 Q86V86 2/20 0.44
PIM1 P11309 2/20 0.40
PIM2 Q9P1W9 2/20 0.40
ALOX5 P09917 2/20 0.39
TNKS O95271 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
ROCK1 Q13464 1/20 0.37
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
XBP1 P17861 1/20 0.37
PTBP1 P26599 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
GALK1 P51570 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993944 1.00 LIMK1 (0.49) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL30258311 0.93 LIMK1 (0.47) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL24171331 0.92 LIMK1 (0.44) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL430157 0.92 LIMK1 (0.48) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL429294 0.92 LIMK1 (0.48) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL19103173 0.91 LIMK1 (0.43) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL19607053 0.91 LIMK1 (0.43) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL15179507 0.91 LIMK1 (0.45) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL13681160 0.90 LIMK1 (0.45) LIMK1PIM3PIM1PIM2ALOX5
SCHEMBL29828845 0.90 TNKS (0.49) LIMK1PIM3PIM1PIM2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 US disclosed
EP-2185532-B1 BENZO-FUSED THIOPHENE COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORP (US) 2016-11-09 EP disclosed
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-12-24 US disclosed
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-12-24 US disclosed
US-9153786-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-10-06 US disclosed
US-20140326977-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2014-11-06 US disclosed
US-20140326977-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2014-11-06 US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 US disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC LIMK1 2156/4885PIM3 356/4885PIM1 444/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC LIMK1 232/4885PIM3 245/4885PIM1 227/4885
US-20150372243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEAD2 LIMK1 457/4885PIM3 496/4885PIM1 553/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 LIMK1 457/4885PIM3 496/4885PIM1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.