SCHEMBL131326

SCHEMBL131326

O=P(NCc1ccc(CNP(=O)(Oc2ccccc2)Oc2ccccc2)cc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.93
MEN1 O00255 9/20 0.93
HTT P42858 3/20 0.93
LMNA P02545 3/20 0.73
MAPT P10636 2/20 0.73
KDM4E B2RXH2 1/20 0.53
L3MBTL1 Q9Y468 3/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
SRC P12931 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21234526 0.87 MEN1 (0.71) KMT2AMEN1HTTLMNAMAPT
SCHEMBL21234322 0.87 KMT2A (0.71) KMT2AMEN1HTTLMNAMAPT
SCHEMBL1108330 0.87 MEN1 (0.83) KMT2AMEN1HTTLMNAMAPT
SCHEMBL133338 0.81 MEN1 (0.84) KMT2AMEN1HTTLMNAMAPT
SCHEMBL1108327 0.78 MEN1 (0.65) KMT2AMEN1HTTLMNAMAPT
SCHEMBL17109337 0.76 MEN1 (0.61) KMT2AMEN1HTTLMNAMAPT
SCHEMBL4836574 0.76 MEN1 (0.61) KMT2AMEN1HTTLMNAMAPT
SCHEMBL26967789 0.76 MEN1 (0.61) KMT2AMEN1HTTLMNAMAPT
SCHEMBL133339 0.75 LMNA (0.56) KMT2AMEN1HTTLMNAMAPT
SCHEMBL9414571 0.74 KDM4E (0.65) KMT2AMEN1HTTLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1452567-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-03-07 EP disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 EP disclosed
US-7411013-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2008-08-12 US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
US-7115677-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-10-03 US disclosed
US-20060074154-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-04-06 US disclosed
US-20040266916-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-30 US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1452567-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-09-01 EP disclosed