SCHEMBL133338

SCHEMBL133338

Cc1ccc(OP(=O)(NCc2ccc(CNP(=O)(Oc3ccc(C)cc3)Oc3ccc(C)cc3)cc2)Oc2ccc(C)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.84
KMT2A Q03164 6/20 0.84
LMNA P02545 2/20 0.84
MAPT P10636 2/20 0.84
HTT P42858 2/20 0.64
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
NPSR1 Q6W5P4 1/20 0.46
HSP90AA1 P07900 1/20 0.45
GAA P10253 1/20 0.45
MAPK14 Q16539 1/20 0.43
ALDH1A1 P00352 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131326 0.81 KMT2A (0.93) MEN1KMT2ALMNAMAPTHTT
SCHEMBL28930187 0.79 MEN1 (0.59) MEN1KMT2ALMNAMAPTHTT
SCHEMBL131030 0.77 MEN1 (0.54) MEN1KMT2ALMNAMAPTHTT
SCHEMBL28982509 0.76 MEN1 (0.56) MEN1KMT2ALMNAMAPTHTT
SCHEMBL28658509 0.75 CYP3A4 (0.61) MEN1KMT2ALMNAMAPTCYP3A4
SCHEMBL12018588 0.75 KMT2A (0.50) MEN1KMT2ALMNAMAPTHTT
SCHEMBL21234526 0.74 MEN1 (0.71) MEN1KMT2ALMNAMAPTHTT
SCHEMBL21234322 0.74 KMT2A (0.71) MEN1KMT2ALMNAMAPTHTT
SCHEMBL133339 0.72 LMNA (0.56) MEN1KMT2ALMNAMAPTHTT
SCHEMBL7740490 0.72 MEN1 (0.70) MEN1KMT2ALMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1452567-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-03-07 EP disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 EP disclosed
US-7411013-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2008-08-12 US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
US-7115677-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-10-03 US disclosed
US-20060074154-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-04-06 US disclosed
US-20040266916-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-30 US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1452567-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-09-01 EP disclosed