Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132819 | 0.97 | L3MBTL1 (0.47) | SIRT1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13132845 | 0.94 | HDAC3 (0.47) | SIRT1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13132850 | 0.94 | HDAC3 (0.47) | SIRT1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13132821 | 0.92 | HDAC3 (0.47) | SIRT1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13132820 | 0.92 | HDAC3 (0.47) | SIRT1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL13132736 | 0.90 | NPC1 (0.46) | SIRT1LMNAMEN1KMT2AMAPT | |
| SCHEMBL13132566 | 0.88 | NPC1 (0.46) | LMNAL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL13023613 | 0.87 | LMNA (0.46) | LMNAL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL13400502 | 0.86 | KCNK3 (0.50) | LMNAL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL13023070 | 0.85 | LMNA (0.47) | LMNAL3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | SIRT1 17/4885LMNA 1650/4885L3MBTL1 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.