SCHEMBL13133372

SCHEMBL13133372

CN(C)c1ccc(C=Cc2n(C)c3ccccc3[n+]2C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 8/20 0.57
▸ HTT P42858 8/20 0.57
▸ LMNA P02545 5/20 0.57
▸ KDM4E B2RXH2 2/20 0.57
▸ INSR P06213 4/20 0.52
▸ MEN1 O00255 8/20 0.51
▸ KMT2A Q03164 8/20 0.51
▸ NPSR1 Q6W5P4 6/20 0.51
▸ MAPT P10636 6/20 0.51
▸ NPC1 O15118 5/20 0.51
▸ SMN1; SMN2 Q16637 5/20 0.51
▸ POLB P06746 5/20 0.51
▸ PKM P14618 3/20 0.51
▸ THRB P10828 3/20 0.51
▸ MAPK1 P28482 3/20 0.51
▸ RECQL P46063 2/20 0.51
▸ BCHE P06276 2/20 0.51
▸ BLM P54132 2/20 0.51
▸ ACHE P22303 1/20 0.51
▸ RAD52 P43351 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15624210 0.90 APP (0.47) RAB9AHTTLMNAKDM4EINSR
SCHEMBL15624209 0.88 APP (0.51) RAB9AHTTLMNAKDM4EINSR
SCHEMBL3814983 0.86 RAB9A (0.42) RAB9AHTTLMNAKDM4EINSR
SCHEMBL3837492 0.84 RAB9A (0.41) RAB9AHTTLMNAKDM4EINSR
SCHEMBL13294096 0.84 MEN1 (0.42) RAB9AHTTLMNAKDM4EINSR
SCHEMBL3835590 0.84 RAB9A (0.41) RAB9AHTTLMNAKDM4EINSR
SCHEMBL3834682 0.83 RAB9A (0.40) RAB9AHTTLMNAKDM4EINSR
SCHEMBL3834687 0.83 RAB9A (0.40) RAB9AHTTLMNAKDM4EINSR
SCHEMBL4625097 0.83 ERAP1 (0.38) RAB9AHTTLMNAKDM4EMEN1
SCHEMBL20462106 0.81 HTT (0.40) RAB9AHTTLMNAKDM4EINSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170343537-A1 SPECIMEN ANALYZING METHOD, SPECIMEN ANALYZER, AND REAGENT SYSMEX CORPORATION (JP) 2017-11-30 — — US disclosed
US-20160202170-A1 BLOOD ANALYZER, BLOOD ANALYSIS METHOD, AND COMPUTER PROGRAM PRODUCT SYSMEX CORPORATION 2016-07-14 — — US disclosed
US-9116093-B2 Blood analyzer, blood analysis method, and computer program product SYSMEX CORPORATION (JP) 2015-08-25 — — US disclosed
US-20140051071-A1 BLOOD ANALYZER, BLOOD ANALYSIS METHOD, AND COMPUTER PROGRAM PRODUCT SYSMEX CORPORATION (JP) 2014-02-20 — — US disclosed
US-8455209-B2 Reagent and reagent kit for analysis of immature leukocyte SYSMEX CORPORATION (JP) 2013-06-04 — — US disclosed
US-20120282601-A1 BLOOD ANALYZER, BLOOD ANALYSIS METHOD, AND COMPUTER PROGRAM PRODUCT SYSMEX CORPORATION (JP) 2012-11-08 — — US disclosed
US-20100248247-A1 BLOOD ANALYZER AND METHOD FOR DETERMINING EXISTENCE AND NONEXISTENCE OF LYMPHOBLASTS IN BLOOD SAMPLE SYSMEX CORPORATION (JP) 2010-09-30 — — US disclosed
US-20100184061-A1 REAGENT AND REAGENT KIT FOR ANALYSIS OF IMMATURE LEUKOCYTE SYSMEX CORORATION (JP) 2010-07-22 — — US disclosed
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