Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | INSR | P06213 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624210 | 0.97 | APP (0.47) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL13133372 | 0.88 | RAB9A (0.57) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL3814983 | 0.82 | RAB9A (0.42) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL4625097 | 0.82 | ERAP1 (0.38) | RAB9AHTTLMNAKDM4EACHE | |
| SCHEMBL3837492 | 0.80 | RAB9A (0.41) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL3835590 | 0.80 | RAB9A (0.41) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL13294096 | 0.80 | MEN1 (0.42) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL3834687 | 0.79 | RAB9A (0.40) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL3834682 | 0.79 | RAB9A (0.40) | APPRAB9AHTTLMNAKDM4E | |
| SCHEMBL3838343 | 0.75 | MEN1 (0.39) | APPRAB9AHTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014044757-A1 | CATIONIC TRIPHENYLAMINE DERIVATIVES ACTIVABLE BY VISIBLE AND INFRA RED LIGHT FOR INDUCING AND IMAGING APOPTOSIS IN CANCER CELLS | INSTITUT CURIE (FR) | 2014-03-27 | — | — | WO | disclosed |
| EP-2711366-A1 | Cationic triphenylamine derivatives activable by visible and Infra Red light for inducing and imaging apoptosis in cancer cells | Institut Curie (FR) | 2014-03-26 | — | — | EP | disclosed |