Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791794 | 1.00 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL17038504 | 1.00 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL14330719 | 1.00 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL17106898 | 0.98 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL20656700 | 0.98 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL14195555 | 0.98 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL22181919 | 0.98 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL10047618 | 0.98 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL22007110 | 0.98 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL13133813 | 0.97 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853403-B2 | Heterocyclic compound and light-emitting element, light-emitting device, lighting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8853403-B2 | Heterocyclic compound and light-emitting element, light-emitting device, lighting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20130130061-A1 | Heterocyclic Compound and Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130130061-A1 | Heterocyclic Compound and Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8329917-B2 | Heterocyclic compound and light-emitting element, light-emitting device, lighting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-8329917-B2 | Heterocyclic compound and light-emitting element, light-emitting device, lighting device, and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20100244670-A1 | Heterocyclic Compound and Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100244670-A1 | Heterocyclic Compound and Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100244670-A1 | Heterocyclic Compound and Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device Using the Same | CRY1, LAGE3, NR2E3 | NPC1 4412/4885RAB9A 1570/4885MEN1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.