SCHEMBL13143147

SCHEMBL13143147

c1ccc(C2(c3ccccc3)c3ccccc3N(c3ccc4oc5ccc(N6c7ccccc7C(c7ccccc7)(c7ccccc7)c7ccccc76)cc5c4c3)c3ccccc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTGER4 P35408 1/20 0.32
CHRNA7 P36544 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20383374 0.93
SCHEMBL9920585 0.90
SCHEMBL20383145 0.90 PLA2G2A (0.35) ALDH1A1
SCHEMBL22695371 0.89 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL9920533 0.89
SCHEMBL9920550 0.89
SCHEMBL19319644 0.88 CHRNA7 (0.46) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL19270167 0.86 CDK1 (0.31)
SCHEMBL19318142 0.85 CHRNA7 (0.43) KDM4EMEN1NPC1ALDH1A1MAPT
SCHEMBL19270184 0.85 KDM4E (0.39) KDM4ENPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8384068-B2 Use of acridine derivatives as matrix materials and/or electron blockers in OLEDs BASF SE (DE) 2013-02-26 US disclosed
US-8384068-B2 Use of acridine derivatives as matrix materials and/or electron blockers in OLEDs BASF SE (DE) 2013-02-26 US disclosed
EP-2195868-B1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS BASF SE (DE) 2013-01-02 EP disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
WO-2009047147-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS BASF SE (DE) 2009-04-16 WO disclosed