SCHEMBL9920585

SCHEMBL9920585

C[Si](C)(c1ccc2oc3ccc(N4c5ccccc5C(c5ccccc5)(c5ccccc5)c5ccccc54)cc3c2c1)c1ccc2oc3ccc(N4c5ccccc5C(c5ccccc5)(c5ccccc5)c5ccccc54)cc3c2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13143147 0.90 KDM4E (0.33)
SCHEMBL9920533 0.89
SCHEMBL9920550 0.89
SCHEMBL9920551 0.86 KDM4E (0.32)
SCHEMBL20383374 0.84
SCHEMBL19270167 0.82 CDK1 (0.31)
SCHEMBL20383145 0.81 PLA2G2A (0.35)
SCHEMBL22695371 0.80 SMN1; SMN2 (0.33)
SCHEMBL19319644 0.80 CHRNA7 (0.46)
SCHEMBL19270184 0.79 KDM4E (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393819-B9 SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS UDC IRELAND LTD (IE) 2017-12-27 EP disclosed
EP-2393819-B1 SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2017-01-25 EP disclosed
US-9458182-B2 Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics BASF SE (DE) 2016-10-04 US disclosed
US-9458182-B2 Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics BASF SE (DE) 2016-10-04 US disclosed
EP-2651904-B1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-11-12 EP disclosed
US-8362246-B2 Bispyrimidines for electronic applications BASF SE (DE) 2013-01-29 US disclosed
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-14 US disclosed
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-01-19 US disclosed